Healthy

Can Stem Cells from Young People Make Older People Much Stronger?

Stem Cells

A lot of people buy products that promise to delay their frailty. In other words, these people want to feel young for as long as possible. Although there are such products out there, one cannot deny the impact of stem cells.

There are some clinical trials that made use of Mesenchymal stem cells that were derived from young people and then transplanted into older people. By doing this, there are actually no side-effects because the donors were screened to make sure that their cells would be compatible to the one who’s receiving them.

In a study published by the Journals of Gerontology, the firm who’s been developing this kind of therapy, Longeveron, reported that the infusion of stem cells from young people may have a profound impact when transplanted into old people. It may improve their condition manifold than relying on over-the-counter medicines.


According to Keith March, a cardiologist and director for the Center for Regenerative Medicine at the University of Florida, the study that was made by Longeveron is the first of its kind, simply because it is the first one to address frailty- a common trait that is found in older people- and it is also the first research study that made use of mesenchymal stem cells in this way.

One of the co-founders of Longeveron, Joshua Hare, said that they’ve looked at a couple of measures and they were ecstatic to see that the infusion of young mesenchymal stem cells in the bodies of the old people showed a marked improvement in a couple of different organ systems in their body.

To ensure that the results remained the same, the study was done twice with two different groups of people. The results, without a shadow of a doubt, produced the same results.

Frailty

As we age, we are prone to having frailty syndrome. It comes with plenty of symptoms, including slow walking, generally lower levels of energy, weak grip, and a general proclivity to contract various kinds of illnesses.

Just recently, researchers have been postulating the true causes of frailty. Some have stated that it is due to oxidative stress, dysfunctional mitochondria, and inflammation.

Hare said that you can have two 80-year old people- one who is actively playing tennis and one that is confined in a wheelchair. In other words, there is a clear biological difference between the two people.


It was also believed that a drop in stem cell count may also lead to frailty syndrome as well, which is why Hare and his team conducted studies to see if transplanting new stem cells from young people may have a profound impact in their bodies.

Even though Hare’s study was tangible in the sense that it had a lot of participants in it (all showing remarkable results), the question now would be: is it really something relevant to actual real-world use?

Can we finally be able to live longer and more productive lives if we are transplanted with young adult stem cells?